RNA Details
Disease Name
diabetic nephropathy
Tissue
kidney
RNA Symbol
mir-302d
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
NA
Target
NA
Pathway
APELIN SIGNALING PATHWAY
PubMed ID
Title
"CCN2/CTGF increases expression of miR-302 microRNAs, which target the TGFbeta type II receptor with implications for nephropathic cell phenotypes"
Year
2012
Function
miR-302d decreased TGF-beta-induced epithelial mesenchymal transition (EMT) in renal hkc8 epithelial cells and attenuated TGF-beta-induced mesangial production of fibronectin and thrombospondin.